Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CCR1 | P32246 | 5/20 | 0.60 |
| ▸ | CCR8 | P51685 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.60 |
| ▸ | CCR5 | P51681 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.60 |
| ▸ | MMP2 | P08253 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GMNN | O75496 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1543407 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1003398 | 1.00 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL8313 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL6513577 | 0.98 | LMNA (1.00) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL7268962 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL1052095 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL723791 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| Hydrochloric Acid SCHEMBL4917361 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL15788918 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT | |
| SCHEMBL7142651 | 0.96 | LMNA (0.96) | LMNACYP3A4CCR1CCR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311241-B1 | USE OF A POROUS CARRIER | DYTECH CORP LTD (GB) | 2009-01-14 | — | — | EP | disclosed |
| US-20040265350-A1 | Use of a porous carrier | UNIVERSITY OF WARWICK (GB) | 2004-12-30 | — | — | US | disclosed |
| EP-1311241-A2 | USE OF A POROUS CARRIER | DYTECH CORPORATION LIMITED (GB) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002015881-A2 | USE OF A POROUS CARRIER | DYTECH CORPORATION LTD. (GB) | 2002-02-28 | — | — | WO | disclosed |