Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 8/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | CASP2 | P42575 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20620309 | 0.84 | RAB9A (0.73) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL1929165 | 0.82 | NPC1 (0.85) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| Hydrochloric Acid SCHEMBL31228835 | 0.80 | NPC1 (0.82) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL1222245 | 0.80 | KDM4E (0.66) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL6301755 | 0.80 | MEN1 (0.67) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL26333913 | 0.80 | KDM4E (0.60) | KMT2AKDM4ENPC1RAB9ATDP1 | |
| SCHEMBL17206346 | 0.78 | ALDH1A1 (0.74) | MEN1KMT2ACYP2C9CYP2C19KDM4E | |
| SCHEMBL3050069 | 0.77 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9AMAPT | |
| SCHEMBL7394648 | 0.77 | KDM4E (0.66) | MEN1KMT2AKDM4ENPC1RAB9A | |
| SCHEMBL20620075 | 0.77 | ALDH1A1 (0.76) | MEN1KMT2ACYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005563-A1 | METHODS RELATED TO ACTIVATION OF THE BONE MORPHOGENIC PROTEIN SIGNALING PATHWAY | ST. JUDE CHILDREN'S RESEARCH HOSPITAL (US) | 2019-01-03 | — | — | WO | disclosed |