Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 9/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085191 | 0.85 | BRS3 (0.47) | BRS3P2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13477501 | 0.85 | NPC1 (0.48) | BRS3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20620514 | 0.85 | BRS3 (0.44) | BRS3P2RX7TNKS2NPC1RAB9A | |
| SCHEMBL19085342 | 0.83 | BRS3 (0.56) | BRS3NPC1RAB9AMDM2SMN1; SMN2 | |
| SCHEMBL20621045 | 0.83 | BRS3 (0.44) | BRS3P2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19085228 | 0.83 | BRS3 (0.47) | BRS3P2RX7TNKS2SMN1; SMN2 | |
| SCHEMBL13477541 | 0.82 | BRS3 (0.46) | BRS3P2RX7TNKS2NPC1RAB9A | |
| SCHEMBL19085173 | 0.82 | BRS3 (0.44) | BRS3P2RX7TNKS2NPC1RAB9A | |
| SCHEMBL20620617 | 0.82 | BRS3 (0.44) | BRS3P2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20620524 | 0.81 | BRS3 (0.44) | BRS3NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190000832-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | Selder Pharma Inc. (US) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190000832-A1 | TETRAHYDROISOQUINOLIN-1-ONE DERIVATIVE OR SALT THEREOF | BRS3, BDKRB2, NTSR2 | BRS3 1/4885RECQL 1518/4885P2RX7 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.