Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8242416 | 1.00 | KDM4E (0.57) | KDM4EHPGDHSD17B10FAAHMEN1 | |
| SCHEMBL11032123 | 0.94 | FAAH (0.61) | KDM4EHPGDHSD17B10FAAHMEN1 | |
| SCHEMBL8242399 | 0.89 | KDM4E (0.55) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL11486027 | 0.85 | KDM4E (0.55) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL11486031 | 0.85 | KDM4E (0.55) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL15143004 | 0.84 | KMT2A (0.66) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8236092 | 0.84 | KDM4E (0.50) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL8244975 | 0.84 | KDM4E (0.56) | KDM4EHPGDHSD17B10MEN1KMT2A | |
| SCHEMBL16366280 | 0.84 | KDM4E (0.52) | KDM4EHPGDHSD17B10FAAHMEN1 | |
| SCHEMBL23677942 | 0.83 | ADAM17 (0.52) | KDM4EHPGDHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005617-A1 | ANTIBACTERIAL LIPOPEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | Ramapo Pharmaceuticals, Inc. (US) | 2019-01-03 | — | — | WO | disclosed |