Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22572365 | 0.88 | SLC6A2 (0.42) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| SCHEMBL13740722 | 0.83 | AOC3 (0.41) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| SCHEMBL16226673 | 0.82 | AOC3 (0.41) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| SCHEMBL1760781 | 0.76 | OPRD1 (0.50) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| Bromide SCHEMBL11785624 | 0.74 | OPRD1 (0.49) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| SCHEMBL7255569 | 0.72 | HPGD (0.42) | MEN1KMT2AAOC3HPGDNPSR1 | |
| SCHEMBL903669 | 0.72 | HPGD (0.46) | MEN1KMT2AAOC3HPGDNPSR1 | |
| SCHEMBL334729 | 0.71 | ROCK1 (0.39) | MEN1KMT2AAOC3SLC6A2SLC6A4 | |
| Propane SCHEMBL17375310 | 0.69 | MEN1 (0.46) | MEN1KMT2AAOC3IDO1TDO2 | |
| SCHEMBL13126150 | 0.69 | CYP17A1 (0.42) | MEN1KMT2AAOC3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019005883-A1 | COMPOSITIONS AND USES THEREOF | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2019-01-03 | — | — | WO | disclosed |