Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.35 |
| ▸ | BCR | P11274 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598326 | 0.81 | LMNA (0.43) | HSP90AA1ADORA2AADORA1L3MBTL1ALDH1A1 | |
| SCHEMBL20623289 | 0.79 | IRAK4 (0.45) | ADORA2AADORA1KDM4EL3MBTL1NPC1 | |
| SCHEMBL20621570 | 0.73 | ADORA2A (0.48) | HSP90AA1ADORA2AADORA1KDM4EL3MBTL1 | |
| SCHEMBL30501451 | 0.72 | PIM1 (0.45) | HSP90AA1ADORA2AADORA1L3MBTL1ALDH1A1 | |
| SCHEMBL20598264 | 0.72 | PIM1 (0.45) | HSP90AA1ADORA2AADORA1L3MBTL1ALDH1A1 | |
| Water SCHEMBL28379081 | 0.72 | ADORA2A (0.47) | HSP90AA1ADORA2AADORA1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL28380678 | 0.72 | ADORA2A (0.47) | HSP90AA1ADORA2AADORA1KDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL20598299 | 0.71 | ADORA2A (0.46) | HSP90AA1ADORA2AADORA1KDM4EL3MBTL1 | |
| SCHEMBL20598106 | 0.71 | CSF1R (0.57) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL20598590 | 0.70 | CHEK1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019006126-A1 | KINASE INHIBITORS AND METHODS FOR MAKING AND USING | RIGEL PHARMACEUTICALS, INC. (US) | 2019-01-03 | — | — | WO | disclosed |