Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | BCL3 | P20749 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20598264 | 1.00 | PIM1 (0.45) | PIM1PIM3ADORA2AADORA1IRAK4 | |
| SCHEMBL30501459 | 0.87 | PIM1 (0.47) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL20598210 | 0.87 | PIM1 (0.47) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL20598326 | 0.86 | LMNA (0.43) | PIM1PIM3ADORA2AADORA1IRAK4 | |
| SCHEMBL20598757 | 0.84 | PIM1 (0.48) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL30501336 | 0.84 | PIM1 (0.48) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL20598451 | 0.83 | IRAK4 (0.63) | PIM1PIM3ADORA2AADORA1IRAK4 | |
| SCHEMBL30501473 | 0.82 | PIM1 (0.43) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL20598593 | 0.82 | PIM1 (0.43) | PIM1PIM3IRAK4MAPK10ALDH1A1 | |
| SCHEMBL20598509 | 0.82 | IRAK4 (0.46) | PIM1PIM3IRAK4MAPK10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032642-B | Kinase inhibitors and methods of making and using the same | 里格尔药品股份有限公司 | 2023-07-18 | — | — | CN | disclosed |