Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | FADS1 | O60427 | 1/20 | 0.36 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19120677 | 0.85 | AR (0.44) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL19119858 | 0.84 | LRRK2 (0.37) | ARGRM5FADS1 | |
| SCHEMBL20623595 | 0.83 | AR (0.41) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL19120715 | 0.82 | GRM5 (0.34) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL20623411 | 0.81 | AR (0.37) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL19120618 | 0.81 | AR (0.35) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL20623410 | 0.80 | AR (0.39) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL19120637 | 0.78 | GRM5 (0.38) | ARGRM5FADS1 | |
| SCHEMBL19120336 | 0.78 | SQOR (0.35) | ARGRM5FADS1SLC34A1 | |
| SCHEMBL19120175 | 0.77 | FADS1 (0.36) | ARGRM5FADS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10941132-B2 | Pyrazole derivatives | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2021-03-09 | — | — | US | disclosed |
| US-20190002432-A1 | PYRAZOLE DERIVATIVES | HUA MEDICINE (SHANGHAI) LTD. (CN) | 2019-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10941132-B2 | Pyrazole derivatives | GRM5, GRIK5, GRIN2C | AR 2898/4885GRM5 1/4885FADS1 3176/4885 |
| US-20190002432-A1 | PYRAZOLE DERIVATIVES | GRM5, GRIK5, GRIN2C | AR 2898/4885GRM5 1/4885FADS1 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.