Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 9/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 5/20 | 0.59 |
| ▸ | PRKCG | P05129 | 5/20 | 0.59 |
| ▸ | PRKCB | P05771 | 5/20 | 0.59 |
| ▸ | PRKCH | P24723 | 5/20 | 0.59 |
| ▸ | PRKCI | P41743 | 5/20 | 0.59 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.59 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.59 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.59 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.59 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.59 |
| ▸ | CDK4 | P11802 | 4/20 | 0.54 |
| ▸ | CCND1 | P24385 | 4/20 | 0.54 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.54 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.54 |
| ▸ | CDK2 | P24941 | 2/20 | 0.54 |
| ▸ | PRKACA | P17612 | 2/20 | 0.54 |
| ▸ | PRKACG | P22612 | 2/20 | 0.54 |
| ▸ | PRKACB | P22694 | 2/20 | 0.54 |
| ▸ | MYLK | Q15746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20623415 | 0.89 | CDK4 (0.56) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623426 | 0.89 | PRKCG (0.72) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623416 | 0.88 | PRKCA (0.52) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623435 | 0.88 | CDK4 (0.58) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623428 | 0.87 | CDK4 (0.64) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623420 | 0.87 | CDK4 (0.52) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20624166 | 0.85 | PRKCA (0.63) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623449 | 0.84 | CDK4 (0.53) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623417 | 0.84 | PRKCA (0.49) | PRKCAPRKD3PRKCGPRKCBPRKCH | |
| SCHEMBL20623419 | 0.84 | PRKCA (0.51) | PRKCAPRKD3PRKCGPRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019000224-A1 | BISINDOLYLMALEIMIDE DERIVATIVE AND PREPARATION METHOD AND USE THEREOF | 中国海洋大学 | 2019-01-03 | — | — | WO | disclosed |