SCHEMBL20624005

CC(C)(C)c1ccc2c(c1)c1ccccc1n2-c1cc(-c2c(C(F)(F)F)cccc2C(F)(F)F)c(-n2c3ccccc3c3cc(C(C)(C)CCC(C)(C)c4ccc5c6ccccc6n(-c6cc(-c7c(C(F)(F)F)cccc7C(F)(F)F)c(-n7c8ccccc8c8ccc(C(C)(C)C)cc87)cc6C#N)c5c4)ccc32)cc1C#N

nearest known ligand 0.36

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	AR	P10275	10/20	0.36

▸	RORC	P51449	1/20	0.34

▸	KIF11	P52732	1/20	0.33

▸	PTGES	O14684	1/20	0.31

▸	PPARG	P37231	1/20	0.30

▸	PPARA	Q07869	1/20	0.30

▸	SLC22A12	Q96S37	2/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL20611494	0.97	AR (0.35)	ARRORCKIF11PTGES
SCHEMBL21898693	0.93	KIF11 (0.38)	ARRORCKIF11PPARGPPARA
SCHEMBL21898692	0.92	AR (0.34)	ARRORCKIF11
SCHEMBL21898695	0.89	AR (0.36)	ARRORCPPARGPPARA
SCHEMBL20623728	0.87	KIF11 (0.38)	ARRORCKIF11PPARGPPARA
SCHEMBL20623729	0.86	AR (0.38)	ARRORCKIF11PTGESPPARG
SCHEMBL20623788	0.86	KIF11 (0.42)	ARKIF11PPARGPPARA
SCHEMBL20623789	0.86	KIF11 (0.37)	ARRORCKIF11PTGESPPARG
SCHEMBL20611573	0.83	KIF11 (0.36)	ARRORCKIF11PTGESPPARG
SCHEMBL21898841	0.83	TRPA1 (0.35)	ARKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3645523-B1	ORGANIC MOLECULES, ESPECIALLY FOR USE IN OPTOELECTRONIC DEVICES	SAMSUNG DISPLAY CO LTD (KR)	2022-08-03	—	—	EP	disclosed
WO-2019002175-A1	ORGANIC MOLECULES, ESPECIALLY FOR USE IN OPTOELECTRONIC DEVICES	CYNORA GMBH (DE)	2019-01-03	—	—	WO	disclosed