SCHEMBL20626197

SCHEMBL20626197

CCCCOc1cc(OCCCc2c(C)n[nH]c2C)cc(C(=O)O)c1

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TTR P02766 4/20 0.59
▸ ALB P02768 1/20 0.58
▸ PLA2G2A P14555 1/20 0.57
▸ SMN1; SMN2 Q16637 5/20 0.56
▸ MEN1 O00255 3/20 0.56
▸ KMT2A Q03164 3/20 0.56
▸ ALDH1A1 P00352 1/20 0.56
▸ LMNA P02545 5/20 0.55
▸ HSD17B10 Q99714 3/20 0.52
▸ HTT P42858 2/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.48
▸ ATM Q13315 1/20 0.47
▸ PLA2G4B P0C869 1/20 0.45
▸ GAA P10253 1/20 0.44
▸ MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17507483 0.86 TTR (0.55) TTRALBPLA2G2ASMN1; SMN2MEN1
SCHEMBL17495595 0.83 HSD17B10 (0.69) TTRALBSMN1; SMN2MEN1KMT2A
SCHEMBL17522782 0.81 TTR (0.62) TTRALBSMN1; SMN2MEN1KMT2A
SCHEMBL10830829 0.80 PLA2G2A (0.86) PLA2G2AKMT2APLA2G4B
SCHEMBL3077835 0.77 PLA2G2A (0.80) PLA2G2AKMT2APLA2G4B
SCHEMBL17495600 0.75 TTR (0.56) TTRALBSMN1; SMN2MEN1KMT2A
SCHEMBL23352169 0.75 PLA2G2A (0.96) PLA2G2AKMT2APLA2G4B
SCHEMBL28627609 0.75 PLA2G2A (0.77) PLA2G2AKMT2APLA2G4B
SCHEMBL17522787 0.75 SMN1; SMN2 (0.69) TTRALBSMN1; SMN2MEN1KMT2A
SCHEMBL10263820 0.74 PLA2G2A (0.76) PLA2G2AKMT2APLA2G4B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10172959-B2 Systems for stabilizing and delivering active agents Alhamadsheh, Mamoun M. (US) 2019-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10172959-B2 Systems for stabilizing and delivering active agents SERPINA6, SERPINC1, SERPINE1 TTR 67/4885ALB 30/4885PLA2G2A 541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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