Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24168968 | 0.81 | ATM (0.54) | RAB9ANPC1KMT2AGAAKDM4E | |
| SCHEMBL31527768 | 0.79 | ATM (0.77) | RAB9ANPC1KMT2AGAAKDM4E | |
| SCHEMBL2141997 | 0.79 | GAA (0.58) | RAB9AKMT2AGAAKDM4EBLM | |
| SCHEMBL8048675 | 0.79 | NOTUM (0.59) | RAB9AKMT2AGAAKDM4EBLM | |
| SCHEMBL24282083 | 0.79 | KDM4E (0.59) | KMT2AGAAKDM4EBLMMAPT | |
| SCHEMBL12655260 | 0.79 | GAA (0.58) | RAB9AKMT2AGAAKDM4EBLM | |
| SCHEMBL1835068 | 0.77 | GAA (0.56) | RAB9AKMT2AGAAKDM4EBLM | |
| SCHEMBL4968284 | 0.77 | GAA (0.56) | RAB9AKMT2AGAAKDM4EBLM | |
| SCHEMBL57100 | 0.77 | KMT2A (0.44) | RAB9ANPC1KMT2AKDM4EBLM | |
| SCHEMBL25271584 | 0.76 | RAB9A (0.60) | RAB9AKMT2AGAAKDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070085-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-09 | — | — | EP | disclosed |
| CN-105593228-B | Loop coil fused lactams compound for organic electroluminescence device | 默克专利有限公司 | 2018-11-02 | — | — | CN | disclosed |