Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10708809 | 0.87 | ATM (0.60) | GAAKMT2AATMKDM4EBLM | |
| SCHEMBL31527768 | 0.86 | ATM (0.77) | GAAKMT2AATMKDM4EBLM | |
| SCHEMBL8460307 | 0.85 | RAB9A (0.52) | GAAKMT2AATMKDM4EBLM | |
| SCHEMBL2142002 | 0.82 | ALDH1A1 (0.70) | GAAKMT2AKDM4EBLMALDH1A1 | |
| SCHEMBL7029967 | 0.80 | KMT2A (0.52) | KMT2AATMKDM4EBLMALDH1A1 | |
| SCHEMBL29728552 | 0.80 | KMT2A (0.52) | KMT2AATMKDM4EBLMALDH1A1 | |
| SCHEMBL11794672 | 0.79 | KMT2A (0.64) | GAAKMT2AKDM4EALDH1A1HTT | |
| SCHEMBL24282083 | 0.79 | KDM4E (0.59) | GAAKMT2AATMKDM4EBLM | |
| SCHEMBL8048675 | 0.79 | NOTUM (0.59) | GAAKMT2AATMKDM4EBLM | |
| SCHEMBL20627293 | 0.79 | RAB9A (0.63) | GAAKMT2AATMKDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160212993-A1 | ADJUVANT COMPOSITIONS | SYNGENTA LIMITED (GB) | 2016-07-28 | — | — | US | disclosed |
| US-20150313215-A1 | PESTICIDAL MIXTURES | SYNGENTA CROP PROTECTION LLC (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150011573-A1 | ADJUVANT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2015-01-08 | — | — | US | disclosed |
| EP-2811828-A1 | ADJUVANT COMPOSITIONS | Syngenta Participations AG (CH) | 2014-12-17 | — | — | EP | disclosed |
| US-8852618-B2 | Insecticidal mixture containing gamma-cyhalothrin | SYNGENTA LIMITED (GB) | 2014-10-07 | — | — | US | disclosed |
| US-20130203590-A1 | PESTICIDAL MIXTURES | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-08 | — | — | US | disclosed |
| WO-2013110553-A1 | ADJUVANT COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-01 | — | — | WO | disclosed |
| EP-2549878-A2 | PESTICIDAL MIXTURES | Syngenta Participations AG (CH) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011117272-A2 | PESTICIDAL MIXTURES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-09-29 | — | — | WO | disclosed |
| US-7906127-B2 | Insecticidal mixture containing gamma-cyhalothrin | SYNGENTA LIMITED (GB) | 2011-03-15 | — | — | US | disclosed |
| US-20100081714-A1 | INSECTICIDAL MIXTURE CONTAINING GAMMA-CYHALOTHRIN | CLOUGH MARTIN STEPHEN | 2010-04-01 | — | — | US | disclosed |
| EP-2087791-A2 | Insecticidal mixture containing gamma-cyhalothrin | Syngenta Limited (GB) | 2009-08-12 | — | — | EP | disclosed |
| US-20050233986-A1 | Insecticidal mixture containing gamma-cyhalothrin | SYNGENTA LIMITED (GB) | 2005-10-20 | — | — | US | disclosed |
| EP-1414304-A1 | INSECTICIDAL MIXTURE CONTAINING GAMMA-CYHALOTHRIN | Syngenta Limited (GB) | 2004-05-06 | — | — | EP | disclosed |
| WO-2003011031-A1 | INSECTICIDAL MIXTURE CONTAINING GAMMA-CYHALOTHRIN | SYNGENTA LIMITED (GB) | 2003-02-13 | — | — | WO | disclosed |
| EP-1119547-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | Syngenta Limited (GB) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000071785-A2 | 2-CYLCOALKYLCARBONYLCYCLOHEXANE-1,3-DIONE DERIVATIVES AS HERBICIDES | ZENECA LIMITED (GB) | 2000-11-30 | — | — | WO | disclosed |
| WO-2000021928-A1 | SUBSTITUTED PYRROLIDINONE, THIAZOLIDINONE OR OXAZOLIDINONE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2000-04-20 | — | — | WO | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| EP-0063411-B1 | SUBSTITUTED METHANEPHOSHONIC ACID DERIVATIVES, THEIR USE AS HERBICIDES, HERBICIDAL COMPOSITIONS CONTAINING THEM, AND PROCESSES FOR PREPARING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160212993-A1 | ADJUVANT COMPOSITIONS | TLR3, MYD88, ALOX5 | GAA 2438/4885KMT2A 3037/4885ATM 701/4885 |
| US-20150011573-A1 | ADJUVANT COMPOSITIONS | TLR3, MYD88, ALOX5 | GAA 2438/4885KMT2A 3037/4885ATM 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.