Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | LHCGR | P22888 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL830513 | 0.81 | EPHX1 (0.66) | LMNAKMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL23795440 | 0.80 | EPHX1 (0.59) | LMNAKMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL8418545 | 0.80 | ALDH1A1 (0.65) | EPHX1RAB9ACHRNA7ALDH1A1FAAH | |
| SCHEMBL20627048 | 0.76 | RAB9A (0.50) | LMNAKMT2AHPGDHTTSMN1; SMN2 | |
| SCHEMBL13326281 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 | |
| SCHEMBL5749471 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 | |
| SCHEMBL760437 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 | |
| SCHEMBL18544232 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 | |
| SCHEMBL13917140 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 | |
| SCHEMBL5751554 | 0.70 | EPHX1 (0.58) | KMT2AEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070085-B1 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2019-01-09 | — | — | EP | disclosed |