Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.71 |
| ▸ | SRC | P12931 | 6/20 | 0.71 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627046 | 0.90 | NTRK1 (0.63) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL20604001 | 0.86 | FGFR1 (0.73) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL19350877 | 0.84 | FGFR1 (0.80) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL29623749 | 0.84 | FGFR1 (0.80) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL7990149 | 0.84 | FGFR1 (1.00) | FGFR1SRCKDRRAB9AMCHR1 | |
| Hydrochloric Acid SCHEMBL7987479 | 0.83 | FGFR1 (0.98) | FGFR1SRCKDRRAB9ANPC1 | |
| SCHEMBL20603905 | 0.82 | FGFR1 (0.73) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL19350876 | 0.81 | FGFR1 (0.72) | FGFR1SRCNTRK1FLT3KDR | |
| SCHEMBL14368318 | 0.81 | CA12 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL20627764 | 0.79 | FGFR1 (0.49) | FGFR1SRCRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |