Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.63 |
| ▸ | FLT3 | P36888 | 1/20 | 0.63 |
| ▸ | KDR | P35968 | 5/20 | 0.60 |
| ▸ | FGFR1 | P11362 | 8/20 | 0.57 |
| ▸ | SRC | P12931 | 5/20 | 0.57 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | CDK9 | P50750 | 1/20 | 0.46 |
| ▸ | HSF1 | Q00613 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20627495 | 0.90 | FGFR1 (0.71) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL20627759 | 0.87 | NTRK1 (0.66) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL20627764 | 0.81 | FGFR1 (0.49) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL7353127 | 0.79 | LTA4H (0.58) | KCNH2HRH3 | |
| SCHEMBL14656703 | 0.78 | FGFR1 (0.64) | KDRFGFR1ALDH1A1HPGD | |
| SCHEMBL20627045 | 0.78 | FGFR1 (0.49) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL19350865 | 0.76 | FGFR1 (0.55) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL20627063 | 0.76 | FGFR1 (0.55) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL20604001 | 0.76 | FGFR1 (0.73) | NTRK1FLT3KDRFGFR1SRC | |
| SCHEMBL25487479 | 0.76 | SMN1; SMN2 (0.47) | FGFR1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424924-A1 | UREA COMPOUND, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | Ancureall Pharmaceutical (Shanghai) Co., Ltd. (CN) | 2019-01-09 | — | — | EP | disclosed |