Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.30 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187066 | 0.89 | MAPT (0.39) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL13699061 | 0.88 | MAPT (0.40) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL20628602 | 0.85 | HDAC6 (0.35) | HDAC6RORCTP53HTR3EHTR3B | |
| SCHEMBL12956088 | 0.83 | MAPT (0.36) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL26784255 | 0.80 | MAPT (0.41) | ALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL12700543 | 0.79 | KMT2A (0.35) | HDAC6ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL16858263 | 0.77 | CYP1A2 (0.46) | HDAC6RORCTP53ALDH1A1MAPT | |
| SCHEMBL20872019 | 0.77 | CYP1A2 (0.46) | HDAC6RORCTP53ALDH1A1MAPT | |
| SCHEMBL9581080 | 0.77 | CYP1A2 (0.46) | HDAC6RORCTP53ALDH1A1MAPT | |
| SCHEMBL12533861 | 0.77 | CYP1A2 (0.46) | HDAC6RORCTP53ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424907-A2 | CONNECTIONS AND ORGANIC ELECTRONIC DEVICES | Merck Patent GmbH (DE) | 2019-01-09 | — | — | EP | disclosed |