SCHEMBL16858263

SCHEMBL16858263

Clc1cccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.46
TAAR1 Q96RJ0 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
PGR P06401 1/20 0.41
TP53 P04637 3/20 0.41
NPC1 O15118 1/20 0.41
TSHR P16473 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12533861 1.00 CYP1A2 (0.46) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL9581080 1.00 CYP1A2 (0.46) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL20872019 1.00 CYP1A2 (0.46) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL19801911 0.98 CYP1A2 (0.45) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL258156 0.98 MAPT (0.44) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL1702986 0.98 MAPT (0.44) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL512533 0.98 MAPT (0.44) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL15713960 0.96 TAAR1 (0.44) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL20871543 0.93 CYP1A2 (0.41) CYP1A2TAAR1MAPTKDM4EALDH1A1
SCHEMBL23308243 0.92 TAAR1 (0.52) CYP1A2TAAR1MAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230217811-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-06 US disclosed
US-20230217811-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-07-06 US disclosed
US-11641775-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2023-05-02 US disclosed
US-11641775-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2023-05-02 US disclosed
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-05-20 US disclosed
US-10944058-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2021-03-09 US disclosed
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-09-10 US disclosed
WO-2019066250-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2019-04-04 WO disclosed
EP-3424907-A2 CONNECTIONS AND ORGANIC ELECTRONIC DEVICES Merck Patent GmbH (DE) 2019-01-09 EP disclosed
EP-2875004-B1 FLUORENES AND ELECTRONIC DEVICES CONTAINING THEM MERCK PATENT GMBH (DE) 2018-07-18 EP disclosed
US-20180097178-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-05 US disclosed
US-20180097178-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-04-05 US disclosed
US-9882142-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-9882142-B2 Compounds and organic electronic devices MERCK PATENT GMBH (DE) 2018-01-30 US disclosed
US-20150179940-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-25 US disclosed
US-20150179940-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10944058-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885
US-20230217811-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885
US-20210151682-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885
US-11641775-B2 Compounds and organic electronic devices ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885
US-20200287140-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF OR51E2, PIEZO1, OR10J3 CYP1A2 556/4885TAAR1 2842/4885MAPT 2612/4885
US-20180097178-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885
US-20150179940-A1 COMPOUNDS AND ORGANIC ELECTRONIC DEVICES ETV6, CYP2C19, AFF2 CYP1A2 41/4885TAAR1 2112/4885MAPT 1886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.