Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 19/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15053245 | 0.89 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL15057605 | 0.87 | PTGER1 (0.40) | PTGER1CYP1A2HDAC2 | |
| SCHEMBL15057535 | 0.82 | PTGER1 (0.43) | PTGER1CYP1A2 | |
| SCHEMBL15076168 | 0.75 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL20629007 | 0.75 | PTGER1 (0.53) | PTGER1CYP1A2 | |
| SCHEMBL15057809 | 0.74 | KDM4E (0.43) | PTGER1 | |
| SCHEMBL15076243 | 0.73 | ALDH1A1 (0.40) | PTGER1CYP1A2 | |
| SCHEMBL15076241 | 0.73 | PLA2G4A (0.41) | PTGER1CYP1A2 | |
| SCHEMBL15057806 | 0.73 | PTGER1 (0.58) | PTGER1CYP1A2 | |
| SCHEMBL15076237 | 0.73 | PTGER1 (0.40) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |