Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 15/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076238 | 0.84 | SLC22A12 (0.43) | PTGER1CYP1A2AKR1B1 | |
| SCHEMBL20628868 | 0.76 | PTGER1 (0.33) | ALDH1A1PTGER1CYP1A2 | |
| SCHEMBL15076261 | 0.76 | SLC22A12 (0.43) | PTGER1CYP1A2 | |
| SCHEMBL15076210 | 0.75 | PTGER1 (0.39) | ALDH1A1PTGER1CYP1A2 | |
| SCHEMBL15076244 | 0.74 | PTGER1 (0.44) | PTGER1CYP1A2 | |
| SCHEMBL19547233 | 0.72 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL15052158 | 0.70 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL20629022 | 0.70 | PTGER1 (0.35) | PTGER1CYP1A2 | |
| SCHEMBL15050033 | 0.69 | PTGER1 (0.70) | PTGER1CYP1A2 | |
| SCHEMBL15068508 | 0.69 | PTGER1 (0.36) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |