Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 14/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15051955 | 0.78 | PTGER1 (0.43) | PTGER1CYP1A2TP53MAPT | |
| SCHEMBL15052004 | 0.78 | ALDH1A1 (0.53) | PTGER1CYP1A2KDM4ETP53MAPT | |
| SCHEMBL19610448 | 0.77 | PTGER1 (0.40) | PTGER1CYP1A2TP53MAPT | |
| SCHEMBL19547233 | 0.76 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL15052158 | 0.76 | PTGER1 (0.49) | PTGER1CYP1A2 | |
| SCHEMBL15058239 | 0.75 | KDM4E (0.38) | PTGER1CYP1A2KDM4ETDP1LMNA | |
| SCHEMBL15051821 | 0.75 | PTGER1 (0.40) | PTGER1CYP1A2KMT2ASMN1; SMN2 | |
| SCHEMBL15052055 | 0.74 | PTGER1 (0.46) | PTGER1CYP1A2 | |
| SCHEMBL15051963 | 0.74 | PTGDR2 (0.56) | KDM4EMAPTLMNARAB9AKMT2A | |
| SCHEMBL15070182 | 0.73 | PTGER1 (0.56) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797893-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013101598-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | ALLERGAN, INC. (US) | 2013-07-04 | — | — | WO | disclosed |