Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 14/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076241 | 0.79 | PLA2G4A (0.41) | PTGER1CYP1A2 | |
| SCHEMBL15076262 | 0.78 | KDM4E (0.36) | PTGER1CYP1A2 | |
| SCHEMBL20629092 | 0.76 | ALDH1A1 (0.35) | PTGER1ALDH1A1CYP1A2 | |
| SCHEMBL20628799 | 0.76 | PTGER1 (0.39) | PTGER1ALDH1A1RXFP1 | |
| SCHEMBL15076168 | 0.71 | PTGER1 (0.44) | PTGER1ALDH1A1CYP1A2 | |
| SCHEMBL20628633 | 0.70 | RECQL (0.43) | PTGER1ALDH1A1CYP1A2 | |
| SCHEMBL20628787 | 0.70 | PTGDR2 (0.51) | ALDH1A1CYP1A2 | |
| SCHEMBL15058139 | 0.70 | PTGER1 (0.36) | PTGER1CYP1A2 | |
| SCHEMBL15076243 | 0.70 | ALDH1A1 (0.40) | PTGER1ALDH1A1CYP1A2 | |
| SCHEMBL15076280 | 0.70 | PTGER1 (0.41) | PTGER1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424904-A1 | COMPOUNDS ACTING AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE | Allergan, Inc. (US) | 2019-01-09 | — | — | EP | disclosed |