SCHEMBL20629307

SCHEMBL20629307

Cc1c(F)c(F)c(Cc2c(F)c(F)c(F)c(F)c2F)c(F)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.30
TAS1R1 Q7RTX1 1/20 0.30
TAS1R2 Q8TE23 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16544061 0.97 IDH1 (0.32) IDH1TAS1R3TAS1R1TAS1R2
SCHEMBL18650983 0.84
SCHEMBL13804362 0.83 IDH1 (0.32) IDH1
SCHEMBL20377265 0.82 IDH1 (0.34) IDH1
SCHEMBL107094 0.79 TAS1R3 (0.33) TAS1R3TAS1R1TAS1R2
SCHEMBL12247574 0.77
SCHEMBL12256409 0.75 TAS1R3 (0.32) TAS1R3TAS1R1TAS1R2
SCHEMBL926802 0.75 TAS1R3 (0.35) TAS1R3TAS1R1TAS1R2
SCHEMBL13953024 0.75 IMPDH2 (0.36)
SCHEMBL10084429 0.75 TAS1R3 (0.30) TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3425689-B1 CHARGE-TRANSPORTING VARNISH NISSAN CHEMICAL CORP (JP) 2019-10-23 EP disclosed
EP-3425689-A1 CHARGE-TRANSPORTING VARNISH Nissan Chemical Corporation (JP) 2019-01-09 EP disclosed