Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | TACR3 | P29371 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21895900 | 1.00 | LMNA (0.42) | LMNAHTTNPSR1L3MBTL1ELANE | |
| SCHEMBL21896535 | 0.81 | MAOA (0.39) | LMNAHTTNPSR1L3MBTL1MAOA | |
| SCHEMBL6138472 | 0.69 | MAOA (0.48) | HTTMAOAMAOBOPRM1OPRL1 | |
| SCHEMBL11481803 | 0.69 | GRIN1 (0.42) | LMNAHTTELANEMAOAMAOB | |
| SCHEMBL24817597 | 0.69 | LMNA (0.40) | LMNAHTTOPRM1 | |
| SCHEMBL28269258 | 0.68 | HTT (0.37) | LMNAHTTNPSR1L3MBTL1MAOA | |
| SCHEMBL3284001 | 0.68 | ELANE (0.55) | LMNAHTTNPSR1L3MBTL1ELANE | |
| SCHEMBL28538161 | 0.68 | ELANE (0.55) | LMNAHTTNPSR1L3MBTL1ELANE | |
| Hydrochloric Acid SCHEMBL30175029 | 0.68 | MAOA (0.47) | HTTMAOAMAOBOPRM1OPRL1 | |
| SCHEMBL28819418 | 0.67 | LMNA (0.47) | LMNAHTTNPSR1L3MBTL1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3424941-A1 | PRODUCTION METHOD FOR NONCYCLIC PEPTIDE-NUCLEIC ACID COMPLEX HAVING, AT N-TERMINAL, AMINO ACID WITH THIOL GROUP NEAR AMINO GROUP, LIBRARY THEREOF, AND CYCLIC PEPTIDE-NUCLEIC ACID COMPLEX LIBRARY DERIVED FROM SAME | Chugai Seiyaku Kabushiki Kaisha (JP) | 2019-01-09 | — | — | EP | disclosed |