Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30350316 | 0.95 | CYP3A4 (0.69) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL7457674 | 0.95 | CYP3A4 (0.69) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL7685964 | 0.89 | HTT (0.57) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL12325019 | 0.88 | CA9 (0.59) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL17749683 | 0.87 | LCK (0.58) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL6742081 | 0.87 | HTT (0.55) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL29377307 | 0.87 | LCK (0.58) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL30482808 | 0.86 | SRC (0.54) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL17363694 | 0.86 | SRC (0.54) | HTTCYP3A4CA9TSHRLMNA | |
| SCHEMBL24497291 | 0.84 | HTT (0.62) | HTTCYP3A4CA9TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022118186-A1 | SENOTHERAPEUTIC COMPOUND | BIONEXA S.R.L. (IT) | 2022-06-09 | — | — | WO | disclosed |
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |