Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9417797 | 0.92 | CYP3A4 (0.52) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL17363694 | 0.89 | SRC (0.54) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL30482808 | 0.89 | SRC (0.54) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL20630769 | 0.89 | HTT (0.68) | HTTCYP3A4CA9TSHRRAB9A | |
| SCHEMBL1753958 | 0.88 | HTT (0.52) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL13979264 | 0.88 | HTT (0.57) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL27101935 | 0.86 | CA9 (0.51) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL11154634 | 0.85 | HTT (0.64) | HTTCYP3A4CA9SRCTGFBR1 | |
| SCHEMBL7457674 | 0.85 | CYP3A4 (0.69) | HTTCYP3A4CA9TSHRRAB9A | |
| SCHEMBL30350316 | 0.85 | CYP3A4 (0.69) | HTTCYP3A4CA9TSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| US-4289495-A | HAIR DYES, STORAGE STABILITY | L'OREAL (FR) | 1981-09-15 | — | — | US | disclosed |
| US-4185958-A | HAIR DYES | BUGAUT ANDREE | 1980-01-29 | — | — | US | disclosed |