Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17363694 | 1.00 | SRC (0.54) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL7685964 | 0.89 | HTT (0.57) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL9417797 | 0.89 | CYP3A4 (0.52) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL20630769 | 0.86 | HTT (0.68) | HTTCA9CYP3A4LMNATSHR | |
| SCHEMBL2423890 | 0.86 | HTT (0.63) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL1753958 | 0.85 | HTT (0.52) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL3928834 | 0.84 | GAA (0.47) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL22117016 | 0.84 | LCK (0.50) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL12375157 | 0.84 | HTT (0.47) | SRCTGFBR1HTTCA9CYP3A4 | |
| SCHEMBL5435747 | 0.84 | HTT (0.47) | SRCTGFBR1HTTCA9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942523-B | Benzofuran and benzofuran coumarin derivatives, and preparation method and application thereof | 华东师范大学 | 2023-06-09 | — | — | CN | disclosed |