Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 5/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630757 | 0.90 | POLH (0.58) | POLHACE2TOP2AKDM4EMEN1 | |
| SCHEMBL20631318 | 0.87 | POLH (0.67) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20630211 | 0.84 | POLH (0.67) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20630798 | 0.83 | POLH (0.70) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20630738 | 0.83 | POLH (0.70) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20630788 | 0.81 | POLH (0.70) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20631336 | 0.79 | POLH (0.64) | POLHTOP2AKDM4EMEN1MMP1 | |
| SCHEMBL20630949 | 0.79 | POLH (0.68) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL20630991 | 0.79 | POLH (0.77) | POLHKDM4EMEN1MMP1POLB | |
| SCHEMBL20630770 | 0.78 | POLH (0.67) | POLHKDM4EMEN1MMP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |