Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLH | Q9Y253 | 8/20 | 0.68 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | RECQL | P46063 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | MMP1 | P03956 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | APEX1 | P27695 | 2/20 | 0.60 |
| ▸ | BLM | P54132 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SRC | P12931 | 6/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.54 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20630770 | 0.90 | POLH (0.67) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL24497194 | 0.90 | POLH (0.72) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20631318 | 0.89 | POLH (0.67) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630799 | 0.89 | POLH (0.66) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630208 | 0.88 | POLH (0.65) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630753 | 0.88 | POLH (0.64) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630798 | 0.86 | POLH (0.70) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630738 | 0.86 | POLH (0.70) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20631332 | 0.86 | POLH (0.62) | POLHMEN1KMT2AKDM4EPOLB | |
| SCHEMBL20630933 | 0.85 | POLH (0.89) | POLHMEN1KMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008537-A9 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2020-02-20 | — | — | WO | disclosed |
| WO-2019008537-A1 | MEDICAL COMPOUNDS | VERA SALUS RICERCA S.R.L. (IT) | 2019-01-10 | — | — | WO | disclosed |