Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 1/20 | 0.64 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.48 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15923344 | 0.87 | CALM1 (0.59) | F2RL1ALOX5POLBCALM1SMN1; SMN2 | |
| SCHEMBL20632919 | 0.87 | F2RL1 (0.62) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL20632043 | 0.87 | F2RL1 (0.62) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL7329940 | 0.85 | F2RL1 (0.85) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL13041414 | 0.84 | F2RL1 (0.59) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL9664592 | 0.83 | F2RL1 (0.66) | F2RL1ALOX5POLBALDH1A1NFKB1 | |
| SCHEMBL8585437 | 0.83 | F2RL1 (0.66) | F2RL1ALOX5POLB | |
| SCHEMBL20610768 | 0.83 | F2RL1 (0.70) | F2RL1ALOX5POLBCALM1ALDH1A1 | |
| SCHEMBL20221724 | 0.83 | F2RL1 (0.70) | F2RL1ALOX5POLBALDH1A1NFKB1 | |
| SCHEMBL20610761 | 0.82 | F2RL1 (0.60) | F2RL1ALOX5POLBALDH1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019009956-A1 | FE/CU-MEDIATED KETONE SYNTHESIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2019-01-10 | — | — | WO | disclosed |