Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20632922 | 0.92 | KDM4E (0.36) | — | |
| SCHEMBL20632245 | 0.90 | LRRK2 (0.33) | TEK | |
| SCHEMBL20633005 | 0.89 | LMNA (0.38) | — | |
| SCHEMBL20632313 | 0.89 | PHGDH (0.33) | TEK | |
| SCHEMBL20632519 | 0.88 | LRRK2 (0.33) | TEK | |
| SCHEMBL20632430 | 0.88 | HTR2C (0.40) | TEK | |
| SCHEMBL20632193 | 0.86 | FYN (0.37) | — | |
| SCHEMBL20632940 | 0.85 | TEK (0.33) | TEK | |
| SCHEMBL20632750 | 0.84 | GRIN1 (0.37) | GRIN1GRIN2B | |
| SCHEMBL20632664 | 0.84 | KDM1A (0.34) | GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997029-B1 | SUBSTITUTED BRIDGED UREA ANALOGS AS SIRTUIN MODULATORS | GLAXOSMITHKLINE LLC (US) | 2019-01-09 | — | — | EP | disclosed |