Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814194 | 1.00 | PARG (0.35) | PARGBAZ2BCNR2PDE3BPDE3A | |
| SCHEMBL20632275 | 0.87 | PDE3B (0.33) | PARGCNR2PDE3BPDE3A | |
| SCHEMBL29814365 | 0.87 | PDE3B (0.33) | PARGCNR2PDE3BPDE3A | |
| SCHEMBL20632927 | 0.83 | BAZ2B (0.33) | PARGBAZ2BCNR2NPC1RAB9A | |
| SCHEMBL29814438 | 0.83 | BAZ2B (0.33) | PARGBAZ2BCNR2NPC1RAB9A | |
| SCHEMBL17466031 | 0.83 | DDR1 (0.37) | CNR2 | |
| SCHEMBL20632183 | 0.82 | POLB (0.44) | — | |
| SCHEMBL29814246 | 0.82 | POLB (0.44) | — | |
| SCHEMBL16064951 | 0.82 | PDE2A (0.40) | — | |
| SCHEMBL21933236 | 0.81 | ALDH1A1 (0.32) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2022-08-02 | — | — | US | claimed |
| EP-3649118-B1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2024-08-28 | — | — | EP | disclosed |
| US-20200146294-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-14 | — | — | US | disclosed |
| US-20200146294-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-05-14 | — | — | US | disclosed |
| WO-2019008072-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11399542-B2 | Pesticidally active heterocyclic derivatives with sulfur containing substituents | DDT, CHRM1, ACHE | PARG 3331/4885BAZ2B 3861/4885CNR2 786/4885 |
| US-20200146294-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | DDT, CHRM1, ACHE | PARG 3331/4885BAZ2B 3861/4885CNR2 786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.