Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 9/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.32 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20633533 | 0.84 | — | — | |
| SCHEMBL20609952 | 0.84 | RORC (0.37) | RORCARSTING1AGPAT2ACSS2 | |
| SCHEMBL29814228 | 0.84 | RORC (0.37) | RORCARSTING1AGPAT2ACSS2 | |
| SCHEMBL20936300 | 0.83 | AGPAT2 (0.34) | RORCARSTING1AGPAT2ACSS2 | |
| SCHEMBL20633512 | 0.83 | QRFPR (0.30) | — | |
| SCHEMBL22201177 | 0.81 | — | — | |
| SCHEMBL22201081 | 0.81 | — | — | |
| SCHEMBL22201188 | 0.79 | PTGS2 (0.31) | — | |
| SCHEMBL22201192 | 0.79 | MAPT (0.34) | — | |
| SCHEMBL22683338 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019008072-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-01-10 | — | — | WO | disclosed |