SCHEMBL20633643

SCHEMBL20633643

c1ccc(-n2c3ccccc3c3cc(-c4ccc5c(c4)c4ccccc4n5-c4ccc5c(c4)-c4ccccc4C54c5ccccc5-c5ccccc54)ccc32)cc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ATM Q13315 1/20 0.46
HDAC4 P56524 1/20 0.34
PTGER4 P35408 1/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
TSPO P30536 1/20 0.32
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
PTPN1 P18031 2/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30913098 1.00 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL21138923 0.96 KDM4E (0.39) L3MBTL1KDM4EATMHDAC4EDNRB
SCHEMBL20411906 0.95 KDM4E (0.39) L3MBTL1KDM4EATMHDAC4EDNRB
SCHEMBL22969682 0.95 KDM4E (0.49) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL15087893 0.95 KDM4E (0.49) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL23050948 0.94 KDM4E (0.41) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL17929465 0.94 KDM4E (0.41) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL18779578 0.94 KDM4E (0.43) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL20706761 0.93 KDM4E (0.42) L3MBTL1KDM4EATMHDAC4PTGER4
SCHEMBL20633642 0.92 L3MBTL1 (0.46) L3MBTL1KDM4EATMHDAC4PTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117836-A1 ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-06-29 WO disclosed
EP-4186898-A1 COMPOSITION FOR ORGANIC ELECTRONIC COMPOUNDS Merck Patent GmbH (DE) 2023-05-31 EP disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2023-05-18 US disclosed
US-20230045531-A1 NOVEL ORGANOMETALLIC COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC CO., LTD. (KR) 2023-02-09 US disclosed
EP-3649213-B1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2021-06-23 EP disclosed
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-23 US disclosed
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-07-09 US disclosed
WO-2019233904-A1 ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2019-12-12 WO disclosed
WO-2019007867-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2019-01-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230045531-A1 NOVEL ORGANOMETALLIC COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME ODC1, ORMDL3, ALDH1A2 L3MBTL1 754/4885KDM4E 2462/4885ATM 2879/4885
US-20200216391-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO4C1, SLCO2A1 L3MBTL1 3718/4885KDM4E 3376/4885ATM 4360/4885
US-20230150987-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 L3MBTL1 3258/4885KDM4E 3745/4885ATM 4632/4885
US-20200231578-A1 COMPOSITION FOR ORGANIC ELECTRONIC DEVICES SLCO2B1, SLCO2A1, SLCO1B3 L3MBTL1 3258/4885KDM4E 3745/4885ATM 4632/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.