Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.49 |
| ▸ | CTSV | O60911 | 3/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | AS3MT | Q9HBK9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635509 | 0.80 | MAOA (0.49) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL20634781 | 0.79 | HDAC6 (0.55) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL17500200 | 0.79 | HDAC6 (0.55) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL22467817 | 0.79 | HDAC6 (0.55) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL22467798 | 0.75 | HDAC6 (0.48) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL7842572 | 0.73 | TRPM8 (0.54) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL5879349 | 0.72 | CYP1A2 (0.53) | ACHEMAPTTRPM8KDM4ELMNA | |
| SCHEMBL5879315 | 0.71 | MAOB (0.54) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL4257206 | 0.71 | MAPKAPK2 (0.72) | MAOAMAOBMAPKAPK2CTSVCTSL | |
| SCHEMBL18796679 | 0.70 | MAOA (0.62) | MAOAMAOBCTSVCTSLTRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019007836-A1 | NOVEL HDAC6 INHIBITORS, WITH IMPROVED SOLUBILITY AND THEIR USES | UNIVERSITÄT REGENSBURG (DE) | 2019-01-10 | — | — | WO | disclosed |