Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4128462 | 1.00 | CYP1A2 (0.31) | CYP1A2ALDH1A1 | |
| SCHEMBL13615116 | 0.71 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL9391239 | 0.70 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL9391229 | 0.70 | CYP1A2 (0.37) | CYP1A2 | |
| SCHEMBL14434790 | 0.68 | ESR2 (0.31) | — | |
| SCHEMBL9347679 | 0.65 | ALDH1A1 (0.33) | CYP1A2ALDH1A1 | |
| SCHEMBL9785326 | 0.64 | ALDH1A1 (0.35) | CYP1A2ALDH1A1 | |
| SCHEMBL8997261 | 0.64 | ALDH1A1 (0.35) | CYP1A2ALDH1A1 | |
| SCHEMBL9785318 | 0.64 | ALDH1A1 (0.35) | CYP1A2ALDH1A1 | |
| SCHEMBL9352059 | 0.64 | ALDH1A1 (0.36) | CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148551-B2 | Tricyclic aromatics and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8148551-B2 | Tricyclic aromatics and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-03 | — | — | US | disclosed |
| US-8148551-B2 | Tricyclic aromatics and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2012-04-03 | — | — | US | disclosed |
| US-20090131689-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-05-21 | — | — | US | disclosed |
| US-20090131689-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-05-21 | — | — | US | disclosed |
| US-20090131689-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-05-21 | — | — | US | disclosed |
| WO-2007085297-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007085297-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2007-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131689-A1 | TRICYCLIC AROMATICS AND LIQUID-CRYSTALLINE MEDIUM | CHRM1, C1S, CHRM2 | CYP1A2 67/4885ALDH1A1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.