Sugi Predict

Sugi Predict / Compounds / SCHEMBL20635667

SCHEMBL20635667

SCHEMBL20635667

CC(C)c1cc(F)cc(C(C)C)c1NC(=O)NS(=O)(=O)C1CN(CCC(C)c2cccc(C(C)C)c2NC(=O)NS(=O)(=O)C2CN(C)C2)C1

nearest known ligand 0.47

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GSTO1 P78417 1/20 0.46
▸ NLRP3 Q96P20 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22433550 0.87 GSTO1 (0.41) GSTO1NLRP3
SCHEMBL22433553 0.85 NLRP3 (0.54) NLRP3
SCHEMBL20636116 0.84 GSTO1 (0.41) GSTO1NLRP3
SCHEMBL20635668 0.84 NLRP3 (0.46) GSTO1NLRP3
SCHEMBL20635666 0.83 GSTO1 (0.39) GSTO1
SCHEMBL20636161 0.83 GSTO1 (0.41) GSTO1NLRP3
SCHEMBL22433294 0.81 — —
SCHEMBL22433299 0.80 GSTO1 (0.37) GSTO1NLRP3
SCHEMBL20635800 0.80 GSTO1 (0.38) GSTO1NLRP3
SCHEMBL20636114 0.78 GSTO1 (0.40) GSTO1NLRP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019008025-A1 NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS INFLAZOME LIMITED (IE) 2019-01-10 — — WO disclosed
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