Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 12/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202847 | 0.75 | MPO (0.38) | MPOHPGDALDH1A1KDM4ECYP2C9 | |
| SCHEMBL20636588 | 0.74 | MPO (0.41) | MPOPDE10A | |
| SCHEMBL203140 | 0.70 | HPGD (0.42) | MPOHPGDALDH1A1KDM4ECYP2C9 | |
| SCHEMBL27359756 | 0.61 | PDE10A (0.38) | MPOALDH1A1PDE10AMEN1KMT2A | |
| SCHEMBL204581 | 0.61 | MPO (0.38) | MPOHPGDALDH1A1KDM4ECYP2C9 | |
| SCHEMBL31430260 | 0.61 | MAPK8 (0.40) | HPGDALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1036131 | 0.60 | CCR10 (0.33) | KDM4E | |
| SCHEMBL17713409 | 0.60 | TAAR1 (0.47) | KMT2A | |
| SCHEMBL27889426 | 0.59 | PRNP (0.41) | MPOALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL204878 | 0.58 | MCL1 (0.39) | MPOHPGDALDH1A1KDM4ECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428148-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |