Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20636587 | 0.74 | MPO (0.40) | MPOPDE10A | |
| SCHEMBL202847 | 0.70 | MPO (0.38) | MPOPDE10A | |
| SCHEMBL16596064 | 0.64 | RET (0.36) | MPOPDE10A | |
| SCHEMBL203140 | 0.62 | HPGD (0.42) | MPO | |
| SCHEMBL27359756 | 0.60 | PDE10A (0.38) | MPOPDE10A | |
| SCHEMBL27167495 | 0.60 | HTT (0.37) | MPOPDE10A | |
| SCHEMBL26266060 | 0.58 | MPO (0.43) | MPO | |
| SCHEMBL27889426 | 0.58 | PRNP (0.41) | MPO | |
| SCHEMBL17839887 | 0.57 | NLRP3 (0.39) | PDE10A | |
| SCHEMBL30258631 | 0.56 | PDGFRA (0.35) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428148-A1 | ARYLOAZOL-2-YL CYANOETHYLAMINO COMPOUNDS, METHOD OF MAKING AND METHOD OF USING THEREOF | Merial, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |