Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | STAT1 | P42224 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20636699 | 0.83 | POLB (0.44) | POLBMAOBMAPK14ALDH1A1NPC1 | |
| SCHEMBL24868761 | 0.82 | POLB (0.41) | POLBMAOBMAPK14ALDH1A1NPC1 | |
| SCHEMBL20636704 | 0.78 | POLB (0.40) | POLBALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL20636693 | 0.77 | POLB (0.41) | POLBMAOBALDH1A1NPC1RAB9A | |
| SCHEMBL19711963 | 0.76 | POLB (0.40) | POLBMAOBALDH1A1MEN1KMT2A | |
| SCHEMBL20636697 | 0.75 | POLB (0.42) | POLBALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19993455 | 0.74 | POLB (0.40) | POLBALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL24868774 | 0.74 | POLB (0.40) | POLBMAOBALDH1A1NPC1RAB9A | |
| SCHEMBL23956549 | 0.73 | POLB (0.37) | POLBALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL19711946 | 0.73 | POLB (0.41) | POLBALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-07-16 | — | — | US | disclosed |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-01-28 | — | — | US | disclosed |
| EP-3428166-A1 | CONDENSED HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Corporation (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4343/4885MAOB 1373/4885MAPK14 3602/4885 |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | CHRM1, HCRTR1, NR4A1 | POLB 4742/4885MAOB 1676/4885MAPK14 3378/4885 |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4393/4885MAOB 1431/4885MAPK14 3649/4885 |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NR4A1, CHRM1, NR1D2 | POLB 4393/4885MAOB 1431/4885MAPK14 3649/4885 |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4297/4885MAOB 1322/4885MAPK14 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.