Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | RORC | P51449 | 5/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25251710 | 0.90 | POLB (0.39) | POLBGAARXFP1KMT2AATM | |
| SCHEMBL20636718 | 0.87 | POLB (0.37) | POLBGAARXFP1HTTPTGDR2 | |
| SCHEMBL25259109 | 0.86 | MAPT (0.39) | POLBGAARXFP1KMT2A | |
| SCHEMBL25256194 | 0.81 | POLB (0.36) | POLBGAARXFP1CA2DDR1 | |
| SCHEMBL20636705 | 0.78 | KMT2A (0.37) | POLBKMT2AATMHTTPTGDR2 | |
| SCHEMBL25249590 | 0.77 | RXFP1 (0.38) | POLBGAARXFP1RORC | |
| SCHEMBL23388102 | 0.77 | MIF (0.39) | GAAKMT2AHTT | |
| SCHEMBL20636708 | 0.71 | POLB (0.37) | POLBKMT2AATMHTTPTGDR2 | |
| SCHEMBL19711988 | 0.71 | USP7 (0.39) | POLBGAARXFP1KMT2AATM | |
| SCHEMBL20636714 | 0.70 | HTT (0.36) | KMT2AHTTPTGDR2DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-09-01 | — | — | US | disclosed |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-07-16 | — | — | US | disclosed |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-05-05 | — | — | US | disclosed |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NISSAN CHEMICAL CORPORATION (JP) | 2020-03-26 | — | — | US | disclosed |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NISSAN CHEMICAL CORPORATION (JP) | 2020-01-28 | — | — | US | disclosed |
| EP-3428166-A1 | CONDENSED HETEROCYCLIC COMPOUND AND PEST CONTROL AGENT | Nissan Chemical Corporation (JP) | 2019-01-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10759815-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4343/4885GAA 4345/4885RXFP1 705/4885 |
| US-20200223868-A1 | CONDENSED HETEROCLYCLIC COMPOUNDS AND PESTICIDES | CHRM1, HCRTR1, NR4A1 | POLB 4742/4885GAA 2399/4885RXFP1 504/4885 |
| US-10544163-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4393/4885GAA 4363/4885RXFP1 710/4885 |
| US-20200095263-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AND PESTICIDES | NR4A1, CHRM1, NR1D2 | POLB 4393/4885GAA 4363/4885RXFP1 710/4885 |
| US-10640518-B2 | Condensed heterocyclic compounds and pesticides | NR4A1, CHRM1, NR1D2 | POLB 4297/4885GAA 4352/4885RXFP1 723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.