SCHEMBL2064170

SCHEMBL2064170

O=C(Cl)C1CCC(C(=O)Cl)(C(=O)Cl)C1

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GRM2 Q14416 2/20 0.32
GRM3 Q14832 2/20 0.32
GRM4 Q14833 2/20 0.32
CYP1A2 P05177 1/20 0.32
ALOX15 P16050 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
LMNA P02545 1/20 0.32
GRM5 P41594 1/20 0.32
MTOR P42345 1/20 0.32
GRM1 Q13255 1/20 0.32
PLCB1 Q9NQ66 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8202306 0.80 CYP2C19 (0.32) CYP2C19
SCHEMBL11425483 0.75 GAA (0.36) TDP1TSHR
SCHEMBL28509148 0.73
SCHEMBL4303990 0.73 GRM2 (0.32) GRM2GRM3GRM4CYP1A2ALOX15
SCHEMBL8179932 0.67 GRM2 (0.32) GRM2GRM3GRM4CYP1A2ALOX15
SCHEMBL167272 0.67 EPHX2 (0.34) GRM2GRM3GRM4CYP1A2ALOX15
SCHEMBL6628367 0.67 APLNR (0.37) GRM2GRM3GRM4CYP1A2ALOX15
SCHEMBL7619821 0.67
SCHEMBL30723103 0.65
SCHEMBL19549500 0.65 GRM4 (0.57) GRM2GRM3GRM4CYP1A2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5254261-A Water permeable polyimides or polyamideimides HYDRANAUTICS (US) 1993-10-19 US claimed
EP-2833990-B1 METHOD OF PREPARATION OF A THIN FILM COMPOSITE REVERSE OSMOSIS MEMBRANE WITH ANTIFOULING PROPERTIES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-03-30 EP disclosed
US-20150328592-A1 THIN FILM COMPOSITE RESERVE OSMOSIS MEMBRANE WITH ANTIFOULING PROPERTIES AND METHOD OF PREPARATION OF THE SAME COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-11-19 US disclosed
US-20120255898-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH & DEVELOPMENT, INC. (US) 2012-10-11 US disclosed
US-8147735-B2 Semipermeable polymers and method for producing same ELTRON RESEARCH & DEVELOPMENT, INC. (US) 2012-04-03 US disclosed
WO-2010042250-A2 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-04-15 WO disclosed
US-20100006495-A1 SEMIPERMEABLE POLYMERS AND METHOD FOR PRODUCING SAME ELTRON RESEARCH AND DEVELOPMENT, INC. (US) 2010-01-14 US disclosed
US-5254261-A Water permeable polyimides or polyamideimides HYDRANAUTICS (US) 1993-10-19 US disclosed