SCHEMBL8202306

SCHEMBL8202306

O=C(Cl)C1CC(C(=O)Cl)(C(=O)Cl)C1

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2064170 0.80 GRM2 (0.32) CYP2C19
SCHEMBL17893440 0.77 CYP2C19 (0.55) CYP2C19
SCHEMBL11285851 0.72
SCHEMBL5662878 0.72
SCHEMBL11638650 0.69 CYP2C19 (0.40) CYP2C19
SCHEMBL524795 0.68 CYP2D6 (0.30) CYP2C19
SCHEMBL4380987 0.68 CYP2D6 (0.30) CYP2C19
SCHEMBL27340865 0.68 CYP2D6 (0.30) CYP2C19
SCHEMBL890411 0.68 CYP2D6 (0.30) CYP2C19
SCHEMBL23832321 0.67 CYP2C19 (0.39) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0527348-B1 Interfacially synthesized reverse osmosis membranes and processes for preparing the same HYDRANAUTICS (US) 2000-09-27 EP claimed
US-5254261-A Water permeable polyimides or polyamideimides HYDRANAUTICS (US) 1993-10-19 US claimed