Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CDK9 | P50750 | 1/20 | 0.47 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.47 |
| ▸ | CDK11A | Q9UQ88 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.47 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20654767 | 0.83 | KDM4E (0.50) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL4658361 | 0.79 | KDM4E (0.49) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL30590396 | 0.75 | PRKDC (0.50) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL31570599 | 0.75 | SMPD3 (0.53) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL939415 | 0.75 | SMPD3 (0.53) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL4658238 | 0.73 | KDM4E (0.47) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL4326786 | 0.73 | ALDH1A1 (0.70) | MEN1KMT2AALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL21379546 | 0.72 | MAPT (0.70) | GAAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2260066 | 0.72 | GAA (0.49) | KDM4EGAAMAPTMEN1KMT2A | |
| SCHEMBL24195931 | 0.72 | SMPD3 (0.47) | KDM4EGAAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019014547-A1 | FUNCTIONALIZED PYRIDINE CARBAMATES WITH ENHANCED NEUROPROTECTIVE ACTIVITY | TEXAS TECH UNIVERSITY SYSTEM (US) | 2019-01-17 | — | — | WO | disclosed |