Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.61 |
| ▸ | KIF11 | P52732 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | DUT | P33316 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL31502532 | 0.98 | KCNN4 (0.59) | KCNN4KIF11SIGMAR1DUTNAAA | |
| SCHEMBL14288493 | 0.98 | KCNN4 (0.59) | KCNN4KIF11SIGMAR1DUTNAAA | |
| SCHEMBL29788846 | 0.98 | KCNN4 (0.59) | KCNN4KIF11SIGMAR1DUTNAAA | |
| SCHEMBL14288491 | 0.94 | KCNN4 (0.63) | KCNN4KIF11SIGMAR1DUTNAAA | |
| Acetic Acid SCHEMBL23711260 | 0.85 | KCNN4 (0.53) | KCNN4KIF11DUTNAAAEPHX1 | |
| SCHEMBL8961063 | 0.85 | KCNN4 (0.68) | KCNN4KIF11SIGMAR1DUTHTT | |
| SCHEMBL12264133 | 0.85 | KIF11 (0.68) | KCNN4KIF11SIGMAR1DUTALDH1A1 | |
| SCHEMBL21189694 | 0.84 | KCNN4 (0.52) | KCNN4KIF11SIGMAR1DUTNAAA | |
| SCHEMBL23861615 | 0.84 | KCNN4 (0.52) | KCNN4KIF11DUTNAAAALDH1A1 | |
| SCHEMBL8697311 | 0.82 | SIGMAR1 (0.46) | KCNN4SIGMAR1NAAAEPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380567-B1 | MELANIN PRODUCTION INHIBITOR | POLA CHEM IND INC (JP) | 2019-01-16 | — | — | EP | disclosed |