Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HHAT | Q5VTY9 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LHCGR | P22888 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028051 | 0.85 | DRD1 (0.52) | HHATPOLBDRD1MAPK1NPSR1 | |
| SCHEMBL1863899 | 0.85 | DRD1 (0.52) | HHATPOLBDRD1MAPK1NPSR1 | |
| SCHEMBL8026128 | 0.85 | DRD1 (0.52) | HHATPOLBDRD1MAPK1NPSR1 | |
| SCHEMBL20645693 | 0.82 | HHAT (0.43) | HHATPOLBDRD1MAPK1NPSR1 | |
| SCHEMBL21962743 | 0.81 | HHAT (0.43) | HHATPOLBDRD1MAPK1NPSR1 | |
| SCHEMBL20912495 | 0.80 | HHAT (0.70) | HHATPOLBMAPK1NPSR1LHCGR | |
| SCHEMBL20645760 | 0.78 | GHSR (0.35) | NPSR1 | |
| SCHEMBL20912497 | 0.77 | LHCGR (0.57) | HHATPOLBLHCGR | |
| SCHEMBL20912494 | 0.75 | LHCGR (0.60) | HHATPOLBNPSR1LHCGR | |
| SCHEMBL20645759 | 0.73 | SCN4A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011217-A1 | PYRROLO[1,2-B]PYRIDAZINE COMPOUNDS OR PHARMACOLOGICALLY ACCEPTABLE SALTS THEREOF AND USE THEREOF | 中国科学院上海药物研究所 | 2019-01-17 | — | — | WO | disclosed |