Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18775059 | 0.81 | MLYCD (0.37) | MLYCDHDAC4HDAC6 | |
| SCHEMBL117136 | 0.79 | HDAC4 (0.31) | MLYCDHDAC4HDAC6 | |
| SCHEMBL1537971 | 0.78 | MLYCD (0.34) | MLYCDHDAC4HDAC6 | |
| SCHEMBL18762562 | 0.77 | EPHX2 (0.34) | MLYCDEPHX2 | |
| SCHEMBL18762559 | 0.77 | EPHX2 (0.34) | MLYCDEPHX2 | |
| SCHEMBL1515406 | 0.76 | — | — | |
| SCHEMBL6117370 | 0.75 | ALDH1A1 (0.39) | — | |
| SCHEMBL18762431 | 0.75 | HDAC4 (0.30) | HDAC4HDAC6 | |
| SCHEMBL1537976 | 0.75 | ALDH1A1 (0.33) | MLYCDHDAC4HDAC6 | |
| SCHEMBL20640958 | 0.74 | MLYCD (0.34) | MLYCDHDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652178-B1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | HOFFMANN LA ROCHE (CH) | 2024-01-24 | — | — | EP | disclosed |
| WO-2019012063-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2019-01-17 | — | — | WO | disclosed |