Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | STK17B | O94768 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26494561 | 0.95 | GABRA5 (0.51) | KDM4ESTK17BSTK17AGABRA5DRD2 | |
| SCHEMBL29283265 | 0.90 | GABRA5 (0.46) | KDM4ESTK17BSTK17AGABRA5DRD2 | |
| SCHEMBL25030252 | 0.89 | GABRA5 (0.45) | STK17BSTK17AGABRA5DRD2DRD4 | |
| SCHEMBL23992278 | 0.86 | STK17B (0.46) | KDM4ESTK17BSTK17ACA12CA1 | |
| SCHEMBL24992894 | 0.86 | EPHX2 (0.52) | KDM4ESTK17BSTK17AGABRA5DRD2 | |
| SCHEMBL14158944 | 0.84 | ALDH1A1 (0.57) | STK17BSTK17ARAB9ACA12CA1 | |
| SCHEMBL9605525 | 0.84 | MEN1 (0.55) | KDM4ESTK17BSTK17AGABRA5DRD2 | |
| SCHEMBL20649129 | 0.83 | NPC1 (0.58) | RAB9ATDP1MEN1GAAKMT2A | |
| SCHEMBL17623713 | 0.82 | KDM4E (0.47) | KDM4ESTK17BSTK17AGABRA5RAB9A | |
| SCHEMBL16710810 | 0.82 | KDM4E (0.47) | KDM4ESTK17BSTK17AGABRA5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019013790-A1 | ANTIMICROBIAL COMPOUNDS AND USES THEREOF | CURZA GLOBAL, LLC (US) | 2019-01-17 | — | — | WO | disclosed |