Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCA | P06881 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649199 | 0.89 | ATR (0.32) | — | |
| SCHEMBL20649084 | 0.85 | ACVR1 (0.35) | — | |
| SCHEMBL20649343 | 0.84 | — | — | |
| SCHEMBL30183497 | 0.83 | ATR (0.31) | CALCA | |
| SCHEMBL20649145 | 0.83 | ATR (0.31) | CALCA | |
| SCHEMBL20648988 | 0.81 | — | — | |
| SCHEMBL20649153 | 0.81 | LRRK2 (0.39) | — | |
| SCHEMBL30183348 | 0.81 | LRRK2 (0.39) | — | |
| SCHEMBL20649038 | 0.80 | — | — | |
| SCHEMBL20649159 | 0.80 | LRRK2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |