Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20649146 | 0.89 | CALCA (0.31) | — | |
| SCHEMBL20649084 | 0.87 | ACVR1 (0.35) | — | |
| SCHEMBL20649153 | 0.85 | LRRK2 (0.39) | ATRLRRK2SMYD2L3MBTL3L3MBTL1 | |
| SCHEMBL30183348 | 0.85 | LRRK2 (0.39) | ATRLRRK2SMYD2L3MBTL3L3MBTL1 | |
| SCHEMBL30183263 | 0.84 | LRRK2 (0.38) | ATRLRRK2L3MBTL3L3MBTL1 | |
| SCHEMBL20649159 | 0.84 | LRRK2 (0.38) | ATRLRRK2L3MBTL3L3MBTL1 | |
| SCHEMBL20649191 | 0.84 | CDK4 (0.31) | — | |
| SCHEMBL20648988 | 0.83 | — | — | |
| SCHEMBL20649285 | 0.82 | ATR (0.36) | ATRLRRK2SMYD2L3MBTL3L3MBTL1 | |
| SCHEMBL30183031 | 0.82 | ATR (0.36) | ATRLRRK2SMYD2L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011715-A1 | PYRAZOLO-QUINAZOLINE DERIVATIVES AS CHOLINE KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2019-01-17 | — | — | WO | disclosed |